Drug Standards
Sigma Aldrich Fine Chemicals Biosciences Ciprofloxacin impurity A European Pharmacopoeia (EP) Reference Standard | 86393-33-1 | MFCD00792458 |
Ciprofloxacin impurity A European Pharmacopoeia (EP) Reference Standard | Mol Wt: 281.67 | 86393-33-1 | MFCD00792458 |
![Medchemexpress LLC Ethanone, 1-(4-amino-3,5-dichlorophenyl)-2-[(1,1-dimethylethyl)amino]-, hydrochloride (1:1) | 37845-71-9 | 98.3% | 311.64 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000403638-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Ethanone, 1-(4-amino-3,5-dichlorophenyl)-2-[(1,1-dimethylethyl)amino]-, hydrochloride (1:1) | 37845-71-9 | 98.3% | 311.64 | 50 MG
Clenbuterol impurity 1 (HY-33450) is a white to off-white solid with a molecular weight of 311.64 and a purity of 98.26% by HPLC. It is identified by CAS number 37845-71-9 and has the chemical name Ethanone, 1-(4-amino-3,5-dichlorophenyl)-2-[(1,1-dimethylethyl)amino]-, hydrochloride (1:1).
- Purity of 98.26%
- White to off-white solid
- Molecular formula C12H17Cl3N2O
- Stable at room temperature for 3 years
- Stable in solvent for 2 years at -80°C
Medchemexpress LLC Dacomitinib impurity 11 | 5mg
Dacomitinib impurity 11 is an impurity of Dacomitinib (HY-13272)
![Medchemexpress LLC 2-propen-1-one, 1-[4-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]- | 936563-92-7 | 50mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000269182.png-250.jpg)
Medchemexpress LLC 2-propen-1-one, 1-[4-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]- | 936563-92-7 | 50mg
Ibrutinib Impurity 11 is an impurity of Ibrutinib (HY-10997)
Medchemexpress LLC Dacomitinib impurity 12 | 2803451-99-0 | 5mg
Dacomitinib impurity 12 is an impurity of Dacomitinib (HY-13272)
![Medchemexpress LLC 2-propen-1-one, 1-[4-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]- | 936563-92-7 | 10mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000269183.png-250.jpg)
Medchemexpress LLC 2-propen-1-one, 1-[4-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]- | 936563-92-7 | 10mg
Ibrutinib Impurity 11 is an impurity of Ibrutinib (HY-10997)
Medchemexpress LLC 3-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide (palbociclib impurity) | 386273-25-2 | 10mg
Palbociclib impurity 7 is an impurity of Palbociclib (HY-50767)
Medchemexpress LLC Edoxaban impurity 65 | 50mg
Edoxaban Impurity 65 is an impurity of Edoxaban (HY-10264)
Apexbio Technology LLC LGK-974 1243244-14-5 50mg
LGK-974 (CAS 1243244-14-5) is a small molecule inhibitor specifically targeting Porcupine (PORCN) an enzyme essential for the secretion and activity of Wnt proteins LGK-974 inhibits PORCN with an IC50 of approximately 1 nM thus suppressing Wnt signaling pathways as evidenced by dose-dependent reduction in Wnt secretion and downstream AXIN2 expression In cellular assays LGK-974 demonstrated negligible cytotoxicity even at 20 M Animal model studies including MMTV-Wnt1-driven tumors and human head and neck squamous carcinoma (HNSCC) xenografts indicate LGK-974 reduces tumor growth and decreases phosphorylation of LRP6 LGK-974 is thus valuable for investigating PORCN-mediated Wnt signaling and associated cancers
Apexbio Technology LLC Tivantinib (ARQ 197) 905854-02-6 100mg
Tivantinib (ARQ 197 CAS 905854-02-6) is a selective orally bioavailable small molecule inhibitor of the receptor tyrosine kinase c-MET (hepatocyte growth factor receptor) working through a non-ATP-competitive binding mechanism Tivantinib inhibits recombinant human c-MET with a Ki value of approximately 355 nmol/L It also demonstrates modest inhibitory activity against VEGFR-3 Pim-1 calmodulin-dependent kinase II delta and p21-activated kinase 3 In vitro studies reveal cytotoxicity against various human tumor cell lines (EC50 60-600 nmol/L) independent of c-MET gene amplification or MET protein expression Mechanistically it induces mitotic arrest and apoptosis Tivantinib is used experimentally in tumor biology research showing anti-tumor activities across multiple cancer xenograft models
Apexbio Technology LLC Esomeprazole Sodium 161796-78-7 50mg
Esomeprazole Sodium the S-enantiomer of omeprazole functions pharmacologically as a proton pump inhibitor (PPI) modulating gastric acid secretion through selective inhibition of the H /K -ATPase enzyme in gastric parietal cells By irreversibly binding covalently to the sulfhydryl groups of this enzyme esomeprazole sodium suppresses gastric acid secretion thus serving as an experimental tool in biomedical research exploring acid-related gastrointestinal conditions including erosive esophagitis and gastroesophageal reflux disease (GERD) Reported IC50 values for inhibition of H /K -ATPase activity range approximately from 2 8 M highlighting usage in studies investigating gastric acid regulation and related signaling pathways at the molecular and cellular level
Medchemexpress LLC Taprenepag isopropyl | 1005549-94-9 | 99.0% | 520.60 | 1 ML
Taprenepag isopropyl is a highly selective EP2 receptor agonist. It reduces intraocular pressure (IOP) in the right (dosed) eye in a dose-dependent manner in cynomolgus monkeys. In a high-dose group (0.75 mg/day), IOP was reduced to less than 4 mm Hg on Days 22 and 29. No clinical signs or changes in body weight were observed with any dose, and no ocular findings occurred in the low-dose group (0.75 mg/day).
- Highly selective EP2 receptor agonist.
- Reduces intraocular pressure (IOP) in a dose-dependent manner.
- Achieved IOP reduction to less than 4 mm Hg in high-dose group.
- No clinical signs or changes in body weight observed.
- No ocular findings occurred in the low-dose group.
- Target: EP2.
Cayman Chemical RacecadotrIl 500mg
A prodrug form of thiorphan; reduces or prevents castor oil-induced diarrhea without delaying intestinal transit in rats at 80 or 100 mg/kg, respectively; decreases duration of diarrhea and increases body weight gain in a neonatal gnotobiotic pig model of human rotavirus-induced diarrhea
Medchemexpress LLC 4-quinazolinamine, N-(3-chloro-2-fluorophenyl)-7-methoxy-6-nitro | 1454307-45-9 | 25mg
Dacomitinib impurity 14 is an impurity of Dacomitinib (HY-13272)